Mart Saarma Selected Research

DCC Receptor

1/2021

Netrin-1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson's disease features.

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Mart Saarma Research Topics

Disease

43	Parkinson Disease (Parkinson's Disease) 01/2024 - 02/2007
10	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2022 - 04/2010
3	Inflammation (Inflammations) 01/2024 - 12/2014
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023 - 02/2007
3	Alzheimer Disease (Alzheimer's Disease) 09/2020 - 09/2015
3	Multiple Endocrine Neoplasia Type 2b (MEN 3) 08/2011 - 05/2007
2	Body Weight (Weight, Body) 02/2024 - 01/2022
2	Overnutrition 02/2024 - 01/2022
2	Obesity 02/2024 - 01/2022
2	Synucleinopathies 01/2024 - 01/2021
2	Brain Injuries (Brain Injury) 01/2023 - 07/2009
2	Stroke (Strokes) 01/2023 - 01/2014
2	Nervous System Diseases (Neurological Disorders) 01/2021 - 04/2016
2	Retinal Degeneration 12/2020 - 09/2020
2	Neuralgia (Stump Neuralgia) 09/2020 - 01/2017
2	Infarction (Infarctions) 01/2014 - 07/2009
2	Neoplasms (Cancer) 07/2009 - 05/2007
1	Weight Loss (Weight Reduction) 02/2024
1	Malaria 02/2024
1	Nausea 02/2024
1	Ischemic Stroke 01/2023
1	Edema (Dropsy) 01/2023
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2023
1	Weight Gain 01/2022
1	Proteostasis Deficiencies 01/2022
1	Diabetes Mellitus 12/2020
1	Wolfram Syndrome (Syndrome, Wolfram) 12/2020
1	Multiple Endocrine Neoplasia Type 2a (MEN 2) 02/2020
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020
1	Cognitive Dysfunction 11/2019
1	Enterocolitis 01/2019
1	Hirschsprung Disease (Hirschsprung's Disease) 01/2019
1	Hyperalgesia 01/2018
1	Mental Disorders (Mental Disorder) 01/2017
1	Hypersensitivity (Allergy) 01/2017
1	Neuroinflammatory Diseases 04/2016
1	Leukemia 01/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2016
1	Ischemia 01/2014
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2014
1	Acquired Immunodeficiency Syndrome (AIDS) 02/2013

Drug/Important Bio-Agent (IBA)

31	Nerve Growth Factors (Neurotrophins)IBA 01/2024 - 07/2009
30	Dopamine (Intropin)FDA LinkGeneric 01/2023 - 02/2007
22	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 02/2024 - 02/2007
9	Proteins (Proteins, Gene)FDA Link 01/2024 - 05/2007
9	Oxidopamine (6 Hydroxydopamine)IBA 11/2020 - 07/2007
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2023 - 01/2019
4	Messenger RNA (mRNA)IBA 07/2009 - 04/2005
3	Therapeutic UsesIBA 01/2023 - 09/2015
3	Glial Cell Line-Derived Neurotrophic Factors (GDNF Family Ligands)IBA 01/2019 - 01/2011
3	NeurturinIBA 01/2019 - 02/2007
3	Neuroprotective AgentsIBA 01/2016 - 07/2009
3	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 08/2011 - 05/2007
2	Growth Differentiation Factor 15IBA 02/2024 - 01/2022
2	NeurotoxinsIBA 01/2023 - 08/2011
2	SynucleinsIBA 01/2021 - 01/2017
2	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2017 - 06/2008
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2012 - 08/2011
1	ArtesunateIBA 02/2024
1	GhrelinIBA 02/2024
1	artemisinin (artemisinine)IBA 02/2024
1	alpha-SynucleinIBA 01/2024
1	Phenobarbital (Luminal)FDA Link 01/2024
1	Heme (Haem)IBA 01/2023
1	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 01/2023
1	Collagenases (Collagenase)FDA Link 01/2023
1	Hemoglobins (Hemoglobin)IBA 01/2023
1	Matrix Metalloproteinase 14 (MT1-MMP)IBA 01/2022
1	Matrix Metalloproteinases (MMPs)IBA 01/2022
1	Appetite Depressants (Anorectics)IBA 01/2022
1	DCC ReceptorIBA 01/2021
1	Netrin-1IBA 01/2021
1	Cell Surface ReceptorsIBA 12/2020
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 02/2020
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 11/2019
1	Becaplermin (PDGF-BB)FDA Link 01/2019
1	MucinsIBA 01/2019
1	Platelet-Derived Growth FactorIBA 01/2019
1	Morphine (MS Contin)FDA LinkGeneric 01/2018
1	Protein Isoforms (Isoforms)IBA 01/2018
1	Opioid Analgesics (Opioids)IBA 01/2018
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 04/2016
1	NeuropeptidesIBA 04/2016
1	Phosphotransferases (Kinase)IBA 01/2016
1	lactacystinIBA 12/2015
1	Proteasome InhibitorsIBA 12/2015
1	LigandsIBA 01/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2014
1	Dietary ProteinsIBA 01/2014
1	Chemotactic FactorsIBA 01/2014
1	Amphetamine (Amfetamine)FDA LinkGeneric 08/2011
1	persephinIBA 07/2010
1	Thyroid HormonesIBA 12/2009

Therapy/Procedure

5	Therapeutics 01/2023 - 08/2018
1	Deep Brain Stimulation 01/2018
1	Ligation 01/2017
1	Protein-Restricted Diet (Diet, Protein Restricted) 01/2014
1	Vascular Surgical Procedures 01/2014
1	Diet Therapy (Therapy, Diet) 01/2014